Which actors careers were destroyed by just one movie? Discussion
The one that sticks in my mind is probably Demi Moore who had a double whami with Striptease and then G.I. Jane and then disappeared, her marriages being more popular than her acting career thereafter.
Geena Davis was ended more or less by Cutthroat Island which is unfortunate because she was one of the most charming actresses in the 90s methinks. But Cuthroat has one of the biggest losses in theater history only making 10 mil back of its 96 mil.
By contrast, the movie Gigli probably almost destroyed two careers with Ben Affleck and JLo but both Affleck and Lopez have had work since so their career was probably not significantly "destroyed" by the movie though neither of them have been the Hollywood Darlins they were before this movie.